PREPARATION AND CHARACTERIZATION OF ANTIMICROBIAL POLYHERBAL GEL BY UTILIZING PLANT EXTRACTS OF NEEM, TURMERIC AND PIPAL: A REVIEW

Authors

  • Arvind Singh Rameshwaram Institute of Technology and Management Sitapur Road, Lucknow, Uttar Pradesh, India
  • Anjali Mishra Rameshwaram Institute of Technology and Management Sitapur Road, Lucknow, Uttar Pradesh, India

DOI:

https://doi.org/10.53555/bp.v12i1.2476

Keywords:

Polyherbal gel, antimicrobial activity, neem, pipal, gel formulation, characterization, in vitro testing, plant extracts

Abstract

Polyherbal gels have emerged as an effective form of topical formulation due to their synergistic effects from multiple plant extracts, enhancing therapeutic efficacy. This review focuses on the preparation, characterization, and antimicrobial activity of polyherbal gels using neem (Azadirachta indica), turmeric (Curcuma longa), and pipal (Ficus religiosa) as the primary active ingredients. These plants are well-known for their antimicrobial, anti-inflammatory, and healing properties. The review discusses various methods of formulating the gel, including extraction of plant components, gel base preparation, and the combination of these extracts to formulate a stable and effective antimicrobial gel. It also includes the characterization techniques, phytochemical screening, and in vitro testing methods for antimicrobial activity. Furthermore, the review explores the benefits of polyherbal gels, their potential application in skin infections, along with their future prospects in pharmaceutical and cosmetic industries.

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References

Bansal, A., & Mishra, D. (2020). Antibacterial evaluation of polyherbal formulations. Journal of Ethno pharmacology, 256, 112796.

Bharti, K., & Singh, P. (2020). Formulation and characterization of polyherbal gel containing neem and turmeric extracts. Journal of Pharmaceutical and Biomedical Sciences, 11(5), 478-485.

Das, P., & Ghosh, S. (2018). Stability and antimicrobial testing of herbal gel formulations. Journal of Pharmaceutical and Biological Research, 6(2), 210-218.

Gupta, S., & Kumar, D. (2019). Pipal tree: A natural remedy for antimicrobial applications. International Journal of Phytopharmacology, 10(4), 145-153.

Hegde, S., & Patil, S. (2022). Advances in polyherbal gel formulation: A review. International Journal of Drug Development and Research, 14(2), 80-90.

Jindal, P., & Verma, M. (2021). Antimicrobial and antioxidant activity of polyherbal gels: A systematic review. International Journal of Medicinal Chemistry, 32(2), 195-203.

Kaur, G., & Arora, S. (2021). Neem (Azadirachta indica) in pharmaceutical applications: A review. Journal of Herbal Medicine, 21, 100325.

Kumar, A., & Pardeep, P. (2018). Turmeric as a natural antimicrobial agent in pharmaceutical formulations. Pharmaceutical Sciences, 7(2), 33-39.

Kumar, P., & Kaur, H. (2023). Exploring plant-based antimicrobial agents: A novel approach in pharmaceutical research. Journal of Medicinal Plants Research, 17(5), 210-215.

Kumar, R., & Yadav, A. (2022). Recent trends in polyherbal gel-based formulations. Journal of Pharmaceutical Science and Technology, 8(3), 112-120.

Malhotra, S., & Jain, N. (2020). Development and evaluation of polyherbal gel for wound healing. Pharma Research, 11(3), 76-82.

Mishra, R., & Mishra, A. (2021). The potential of neem, turmeric, and pipal in herbal medicine: A review. Herbal Medicine Journal, 8(3), 52-59.

Patel, M., & Shah, P. (2020). Antibacterial potential of neem (Azadirachta indica) leaves in gel formulation. Indian Journal of Pharmaceutical Sciences, 82(1), 107-113.

Rani, P., & Gupta, N. (2021). Use of pipal (Ficus religiosa) in pharmaceutical applications. Journal of Phytopharmacology, 10(6), 207-212.

Rani, S., & Kaur, M. (2022). Polyherbal gel for topical drug delivery: A review. Journal of Advanced Pharmaceutical Research, 13(1), 88-97.

Sharma, R., & Chauhan, N. (2017). Plant-based antimicrobial formulations in drug delivery systems: A review. Phytomedicine, 42, 45-58.

Singh, A., & Yadav, S. (2019). Preparation and characterization of turmeric-based gel for acne treatment. Journal of Cosmetic Science, 70(1), 25-33.

Sharma, A., & Khan, M. (2020). Wound healing properties of polyherbal gels. International Journal of Advanced Pharmaceutical Sciences, 5(3), 115-121.

Vishwakarma, S., & Tiwari, P. (2023). Microbial resistance to herbal gels: An emerging challenge. Frontiers in Microbiology, 14, 893673.

Verma, R., & Sharma, D. (2019). Herbal gels: A review on their formulation, evaluation, and applications. Pharmaceutical Development and Technology, 24(6), 1223-1230.

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Published

2026-03-05

How to Cite

Singh, A., & Mishra, A. (2026). PREPARATION AND CHARACTERIZATION OF ANTIMICROBIAL POLYHERBAL GEL BY UTILIZING PLANT EXTRACTS OF NEEM, TURMERIC AND PIPAL: A REVIEW. International Journal For Research In Biology & Pharmacy, 12(1), 1–5. https://doi.org/10.53555/bp.v12i1.2476