NON-INVASIVE PAPILLARY CARCINOMA VESICULAR VARIANT ON STRUMA OVARII

Authors

  • Zo Irène RAIVOHERIVONY 1Department of Pathology, Joseph Ravoahangy Andrianavalona University Hospital, Antananarivo, Madagascar
  • Andrianina Zinambatosoa Andriambelo Department of Pathology, Soavinandriana Hospital, Antananarivo, Madagascar
  • Nanatenaina Soa Randrianjafisamindrakotroka Chairman of the Department of Pathology, Medical School of Antananarivo, Madagascar

DOI:

https://doi.org/10.69980/bp.v12i1.2523

Keywords:

ovary, papillary carcinoma, struma ovarii, teratoma

Abstract

Struma ovarii is a mature teratoma, accounting for 0.5 to 1% of all ovarian tumors and defined by the presence of more than 50% thyroid tissue within the neoplasm. It may include the same lesions observed in the thyroid, including malignant transformation. Malignant degeneration of a struma ovarii is an extremely rare type of germ cell tumor, observed in 5 to 15% of ovarian teratomas.

We report a case of struma ovarii with malignant transformation observed in a 31-year-old woman.

Downloads

Download data is not yet available.

References

Prat J, Nogales FF, Cao D, Vang R, Carinelli SG, Zaloudek CJ. Monodermal teratomas and somatic type tumors arising from a dermoid cyst. In: Kurman RJ, Carcangiu ML, Herrington CS, Young RH, editors. WHO Classification of Tumours of Female Reproductive Organs. Lyon: IARC Press; 2014. pp. 63–6.

Yoo SC, Chang KH, Lyu MO, Chang SJ, Ryu HS, Kim HS. Clinical characteristics of struma ovarii. J Gynecol Oncol. 2008 Jun;19(2):135–8.

DeSimone CP, Lele SM, Modesitt SC. Malignant struma ovarii: a case report and analysis of cases reported in the literature with focus on survival and I131 therapy. Gynecol Oncol. 2003;89:543–8.

Pick L. Ueber struma thyreoidea aberrata ovarii. Dtsch Medicinalzeitg 1902;35:412

Alvarez DM, Lee V, Bhatt S, Dogra VS. Struma Ovarii with Papillary Thyroid Carcinoma. J Clin Imaging Sci 2011;1:44. Doi : 10.4103/2156-7514.84322

Salman WD, Singh M, and Twaij Z. A Case of Papillary Thyroid Carcinoma in Struma Ovarii and Review of the Literature. Pathology Research International 2010 ; 1-5. ID 352476. doi:10.4061/2010/352476

Yi Zhu, Chang Wang, Guo-Nan Zhang, Yu ShI, Shi-Qiang Xu, Shi-Jun Jia and Rong He. Papillary thyroid cancer located in malignant struma ovarii with omentum metastasis: a case report and review of the literature. World Journal of Surgical Oncology 2016) ; 14 (17) :1 -4

Jerome Rebollos Barrera, Leonido Andrade Manalo, Frances lina Lantion Ang. Papillary thyroid-type carcinoma arising from struma ovarii. BMJ Case Reports 2012; 1 – 4. doi:10.1136/bcr.03.2012.6145

Shaco-Levy R, Fukunaga M, Stewart CJR. Struma ovarii. In WHO Classification of Tumours Editorial Board. Female genital tumours. Lyon (France): International Agency for Research on Cancer; 2020. (WHO classification of tumours series, 5th ed.; vol. 4)

Mehrangiz Hatami, Dwayne Breining, Ricky L. Owers, Giuseppe Del Priore, Gary L. Goldberg. Malignant Struma Ovarii – A Case Report and Review of the Literature. Gynecol Obstet Invest 2008;65:104–107. DOI: 10.1159/000108654

Kano H, Inoue M, Nishino T, Yoshimoto Y, Arima R: Malignant struma ovarii with Graves’ disease. Gynecol Oncol 2000; 79: 508–510.

Nobuko Yasutake, Hirotsugu Noguchi, Yuta Ibayashi, Hiroaki Nakamura, Kazuki Tateishi, Kotaro Yuki, Ryuji Shiina, Shohei Shimajiri, Takuji Fujita. The Smallest Reported Malignant Struma Ovarii: A Case Report. Case Rep Oncol 2018;11:693– 698. DOI: 10.1159/000493254

L. M. Roth and A. I. Karseladze, “Highly differentiated follicular carcinoma arising from struma ovarii: a report of 3 cases, a review of the literature, and a reassessment of so-called peritoneal strumosis,” International Journal of Gynecological Pathology, vol. 27, no. 2, pp. 213–222, 2008.

Makani S, Kim W, Gaba AR . Struma Ovarii with a focus of papillary thyroid cancer: a case report and review of the literature. Gynecol Oncol 2004 ; 94 : 835 – 9

Nikiforov Y.E, Ghossein R.A,Kakudo K, LiVolsi V, Papott M, Randolph G W, Tallini G,Thompson L. D.R, Tuttle R. M. Non-invasive follicular thyroid neoplasm with papillary-like nuclear features. In WHO Classification of Tumours of Endocrine Organs Lyon (France): International Agency for Research on Cancer; 2019. (WHO classification of tumours series, 5th ed.)

Hasleton PS, Kelehan P, Whittaker JS, Burslem RW, Turner L. Benign and malignant struma ovarii. Arch Pathol Lab Med. 1978 Apr;102(4):180-4. PMID: 580711

Mattucci ML, D ellera A, Guerriero A, e t al. M alignant struma ovarii: a case report and review of the literature. J Endocrinol Invest 2007; 30 : 517 – 20

Downloads

Published

2026-02-24

How to Cite

RAIVOHERIVONY, Z. I., Andrianina Zinambatosoa Andriambelo, & Nanatenaina Soa Randrianjafisamindrakotroka. (2026). NON-INVASIVE PAPILLARY CARCINOMA VESICULAR VARIANT ON STRUMA OVARII. International Journal For Research In Biology & Pharmacy, 12(1), 12–15. https://doi.org/10.69980/bp.v12i1.2523

Issue

Vol. 12 No. 1 (2026): International Journal For Research In Biology & Pharmacy (ISSN: 2208-2093)

Section

Articles

License

Copyright (c) 2026 Authors

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Most read articles by the same author(s)