SMALL BOWEL CANCER : EPIDEMIOLOGICAL AND HISTOPATHOLOGICAL CHARACTERISTICS
DOI:
https://doi.org/10.69980/bp.v12i1.2480Keywords:
Adenocarcinoma, GIST, Lymphoma, Small bowel cancer, AnatomopathologicalAbstract
Cancer of the small bowel is rare. Due to the difficulty of exploring this part of the digestive tract, tumors are often diagnosed at advanced stage. The aim of this study was to determine the epidemiological and anatomopathological aspects of small bowel cancers in Madagascar. This is a retrospective, monocentric, observational, descriptive study, realized at the Department of Pathology of JRA University Hospital, during 10 years. There were 33 cases, with an average of 49 years and a predominantly female (sex ratio = 0,7). Abdominal mass was the most clinical presentation. Histologically, 61% were adenocarcinoma, 30% of lymphoma and 9% of gastrointestinal stromal tumor.
Downloads
References
Huang J, Chan SC, Fung YC, Mak FY, Lok V, Zhang L, et al. Incidence, Risk Factors, and Temporal Trends of
Small Intestinal Cancer: A Global Analysis of Cancer Registries. Gastroenterology. 2023; 165(3): 600‑12
Mellouki I, Jellali K, Ibrahimi A. Tumors of the small bowel: about 27 cases. Pan Afr Med J. 2018; 30: 13
Schwartz GD, Barkin JS. Small-Bowel Tumors Detected by Wireless Capsule Endoscopy. Dig Dis Sci. 2007; 52(4):
‑30
Raharisolo Vololonantenaina CR, Dina TJN, Ravalisoa A. A rare cancer of the small intestine - 25 cases diagnosed at
the Institut Pasteur de Madagascar from 1992 to 2001. Arch Inst Pasteur Madagascar. 2003; 69(1-2)82-6
Ouedraogo S, Kambire JL, Bere B. Primitive Cancers of small Intestine: Epidemiology, Diagnosis and Treatment in
a Context of Limited Resources. Rev Int Sc Méd Abj. 2022; 24, 1:63-69
Halima A, Maha M, Issam L, Hind M, Hassan E. Les tumeurs malignes primitives de l’intestin grêle: Aspects
cliniques et thérapeutiques de 27 patients. Pan Afr Med J. 2011. Rev Chir Afr. 2017 ; 2(13) 80-85
Thakur M, Vats R, Goel D, Bhalla VP. Jejuno-Ileal tumors: a retrospective study. Int Surg J. 2021; 8(10):3109
Yoo AY, Lee BJ, Kim WS, Kim SM, Kim SH, Joo MK, et al. Clinicopathological Features of Small Bowel Tumors
Diagnosed by Video Capsule Endoscopy and Balloon-Assisted Enteroscopy: A Single Center Experience. Clin
Endosc. 2021; 54(1): 85‑91
Koc N, Uncu D, Karaahmetoglu S. Clinical features and prognostic factors in small bowel tumors: A retrospective
evaluation of eighty cases. Ann Med Res. 2020; 27(1):277
Volume-12| Issue 01 | April 2026 4
Cardoso H, Rodrigues JT, Marques M, Ribeiro A, Vilas-Boas F, Santos-Antunes J, et al. Malignant Small Bowel
Tumors: Diagnosis, Management and Prognosis. Acta Med Port. 2015; 28(4): 448‑56
Zhou ZW, Wan DS, Chen G, Chen YB, Pan ZZ. Primary malignant tumor of the small intestine. World J
Gastroenterol. 1999;5(3):273‑6
Rangiah DS, Cox M, Richardson M, Tompsett E, Crawford M. Small bowel tumours: a 10-year experience in four
Sydney teaching hospitals. J Surg. 2004; 74(9):788‑92
Honda W, Ohmiya N, Hirooka Y, Nakamura M, Miyahara R, Ohno E, et al. Enteroscopic and radiologic diagnoses, treatment, and prognoses of small-bowel tumors. Gastrointest Endosc. 2012; 76(2): 344‑54
Farhat MH, Shamseddine AI, Barada KA. Small Bowel Tumors: Clinical Presentation, Prognosis, and Outcome in
Patients in a Tertiary Care Center. J Oncol. 2008; 2008:212067
Mărgăritescu ND, Ciobanu MO, Nemeş RN, Ghelase ŞM, Pleşea RM, Georgescu I, et al. The morphological profile
of small bowel tumors - our experience. Rom J Morphol Embryol. 2016; 57(4) :1241‑52
Cheung DY, Lee I, Chang DK, Kim JO, Cheon JH, Jang BI, et al. Capsule endoscopy in small bowel tumors: A
multicenter Korean study. J Gastroen Hepatol. 2010; 25(6):1079‑86
Zaaimi Y, Aparicio T, Laurent-Puig P, Taieb J, Zaanan A. Advanced small bowel adenocarcinoma: Molecular
characteristics and therapeutic perspectives. Clin Res Hepatol Gastroenterol. 2016;40(2):154‑60
Williamson JML, Williamson RCN. Small bowel tumors: pathology and management. J Med Assoc Thai. 2014 ;
(1) : 126‑37
Gelsomino F, Balsano R, De Lorenzo S, Garajová I. Small Bowel Adenocarcinoma: From Molecular Insights to
Clinical Management. Curr Oncol. 2022;29(2):1223‑36
Razafindrafara HE, Nomenjanahary L, Andriamampionona TF, Randrianjafisamindrakotroka NS. Les lymphomes
primitifs de l’intestin grêle. Rev med Madag. 2016 ; 6(2) 753-757
Cheung DY, Choi MG. Current advance in small bowel tumors. Clin Endosc. 2011;44(1):13‑21
Williamson JML, Williamson RCN. Small bowel tumors: pathology and management. J Med Assoc Thai. 2014 ;
(1) : 126‑37
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 International Journal For Research In Biology & Pharmacy

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
In consideration of the journal, Green Publication taking action in reviewing and editing our manuscript, the authors undersigned hereby transfer, assign, or otherwise convey all copyright ownership to the Editorial Office of the Green Publication in the event that such work is published in the journal. Such conveyance covers any product that may derive from the published journal, whether print or electronic. Green Publication shall have the right to register copyright to the Article in its name as claimant, whether separately
or as part of the journal issue or other medium in which the Article is included.
By signing this Agreement, the author(s), and in the case of a Work Made For Hire, the employer, jointly and severally represent and warrant that the Article is original with the author(s) and does not infringe any copyright or violate any other right of any third parties, and that the Article has not been published elsewhere, and is not being considered for publication elsewhere in any form, except as provided herein. Each author’s signature should appear below. The signing author(s) (and, in
